Figure 3.
Hematoxylin and eosin staining of scarring E18.5 fetal wounds. Black arrows indicate green vital dye tattoo made at the time of wounding. (A) Wound at 24 h (100×) remains open and an inflammatory cell infiltrate is present (open arrow). (B) Magnified view (200×) of the same incompletely healed wound at 24 h. (C) Wound at 72 h (100×) has no epidermal appendages, consistent with adult-type repair and scar formation. (D) Magnified view (200×) of the wound shown in the (C) demonstrating an inflammatory cell infiltrate and lack of dermal appendages. Reprinted with permission from Beanes et al.3 To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/wound