Figure 9.

Biomarkers of innate immunity in premature infants, full-term infants, and adults. (A, B) Neonates ≤32 weeks of GA had higher levels of involucrin and albumin than full-term infants and adults (p<0.05).⁵² * indicates significant difference from all, and ** from adults. (C) Keratin 1,10,11 was lower in both infant groups than adults. *Indicates significant difference from all. (D) The proinflammatory cytokine IL1α was higher in both infant groups than adults and higher in premature than full-term infants when adjusted for GA. ^#Indicates significant difference from adults, and * from full-term infants. (E) The premature infants had higher levels of the proinflammatory cytokines interleukin 6, interleukin 8, interleukin 1 beta, and monocyte chemotactic protein-1 than full-term infants and adults. ^#Indicates significant difference from full-term infants, and * from all.