Table 3.
Hazard Ratios Based on Cox Regression Analysis of Overall Survival
| Predictor and Effect | Hazard Ratio | P Value |
|---|---|---|
| RECIST | ||
| Partial response vs stable disease | 0.39 (0.09, 1.70) | .211 |
| Progressive vs stable disease | 5.31 (2.34, 12.06) | <.001 |
| Choi | ||
| Partial response vs stable disease | 1.15 (0.55, 2.41) | .708 |
| Progressive vs stable disease | 5.81 (2.40, 14.08) | <.001 |
| MASS | ||
| Favorable vs indeterminate response | 0.47 (0.16, 1.35) | .160 |
| Unfavorable vs indeterminate response | 5.07 (2.22, 11.57) | <.001 |
| LDH (per 100 IU/L increment) | 1.49 (1.22, 1.83) | <.001 |
| LDH and RECIST | ||
| LDH (per 100 IU/L increment) | 1.45 (1.16, 1.80) | .001 |
| Partial response vs stable disease | 0.46 (0.11, 2.02) | .305 |
| Progressive vs stable disease | 4.25 (1.88 9.59) | .001 |
| LDH and Choi | ||
| LDH (per 100 IU/L increment) | 1.51 (1.21 1.88) | <.001 |
| Partial response vs stable disease | 1.25 (0.59, 2.64) | .557 |
| Progressive vs stable disease | 5.22 (2.18, 12.54) | <.001 |
| LDH and MASS | ||
| LDH (per 100 IU/L increment) | 1.44 (1.16, 1.79) | .001 |
| Favorable vs indeterminate response | 0.53 (0.18, 1.56) | .251 |
| Unfavorable vs indeterminate response | 4.08 (1.80, 9.27) | .001 |
Note.—Data in parentheses are 95% CIs.