Figure 6. Extensive interlocus gene conversion between SRGAP2 paralogs.
a) Schematic denotes location and orientation (triangles) of SRGAP2 paralogs on human chromosome 1. Thick colored lines connect SRGAP2 paralogs exhibiting signatures of interlocus gene conversion in the MIP data. Line colors correspond to conversion donors, and each line corresponds to a distinct conversion event. b) Examples of different interlocus gene conversion events (highlighted in yellow). Reported sizes indicate the minimum length of the conversion event based on the MIP data, assuming a single conversion event underlies the conversion signature. All events shown, except for the B to A conversion revealed by two MIPs, were detected by the automated caller.