Table 3.
Percentage of time where serum HE4 levels are >114.8 pM and serum CA125 levels are >35 U/mL in premenopausal and postmenopausal women combined.
| Benign Classification (Pre- and Postmenopausal Women Combined) | N | HE4 > 95% tile | CA125 > 95% tile | P value | ||
|---|---|---|---|---|---|---|
| N | % | N | % | |||
| Ovarian Cysts | 204 | 11 | 5% | 29 | 14% | 0.0027 |
| Germ Cell Tumors (Mature Teratoma) | 67 | 0 | 0% | 14 | 21% | 0.0001 |
| Sex Cord Stromal Tumors (Thecoma, Fibrothecoma) | 25 | 8 | 32% | 13 | 52% | 0.1520 |
| Cystadenoma, Adenofibroma, Cystadenofibroma | 56 | 9 | 16% | 11 | 20% | 0.6217 |
| Serous Epithelial Tumors | 206 | 19 | 9% | 42 | 20% | 0.0014 |
| Mucinous Epithelial Tumors | 67 | 11 | 16% | 12 | 18% | 0.8188 |
| Benign - NOS | 113 | 9 | 8% | 31 | 27% | 0.0001 |
| Endometriosis / Endometriomas | 176 | 1 | 1% | 118 | 67% | 0.0000 |
| Abscess / Hydrosalpinx / PID | 30 | 3 | 10% | 11 | 37% | 0.0146 |
| Fibroid (Leiomyomas) | 61 | 3 | 5% | 16 | 26% | 0.0012 |
| Benign – Other (Normal Ovaries) | 37 | 3 | 8% | 8 | 22% | 0.1023 |
|
| ||||||
| All Benign Tumors | 1042 | 77 | 7% | 305 | 29% | 0.0000 |