Table 4.
Percentage of time where serum HE4 levels are >89.1 pM for premenopausal women and >128 pM for postmenopausal women and serum CA125 levels >35 U/mL in premenopausal and postmenopausal women.
| Benign Classification (Pre- and Postmenopausal Women Combined) | N | HE4 > 95% tile | CA125 > 95% tile | P value | ||
|---|---|---|---|---|---|---|
| N | % | N | % | |||
| Ovarian Cysts | 204 | 16 | 8% | 29 | 14% | 0.0399 |
| Germ Cell Tumors (Mature Teratoma) | 67 | 1 | 1% | 14 | 21% | 0.0004 |
| Sex Cord Stromal Tumors (Thecoma, Fibrothecoma) | 25 | 6 | 24% | 13 | 52% | 0.0414 |
| Cystadenoma, Adenofibroma, Cystadenofibroma | 56 | 11 | 20% | 11 | 20% | 1.0000 |
| Serous Epithelial Tumors | 206 | 16 | 8% | 42 | 20% | 0.0002 |
| Mucinous Epithelial Tumors | 67 | 9 | 13% | 12 | 18% | 0.4759 |
| Benign - NOS | 113 | 10 | 9% | 31 | 27% | 0.0003 |
| Endometriosis / Endometriomas | 176 | 6 | 3% | 118 | 67% | 0.0000 |
| Abscess / Hydrosalpinx / PID | 30 | 4 | 13% | 11 | 37% | 0.0369 |
| Fibroid (Leiomyomas) | 61 | 5 | 8% | 16 | 26% | 0.0083 |
| Benign – Other (Normal Ovaries) | 37 | 2 | 5% | 8 | 22% | 0.0413 |
|
| ||||||
| All Benign Tumors | 1042 | 86 | 8% | 305 | 29% | 0.0000 |