Table 3. Pre-Transplant Characteristics of Patients Who Underwent Transplant Compared by Cirrhosis Status at Heart Transplant Evaluationa.
| Variable | Non-cirrhotic | Cirrhoticb | p-value |
|---|---|---|---|
| (n = 13) | (n = 7) | ||
| Protein losing enteropathy | 6 (46) | 4 (57) | 1 |
| Age at listing, years | 9.6 ± 5.3 | 17.6 ± 2.6 | 0.002c |
| Time from Fontan to listing, months | 48 (28.5–100) | 184 (146–187) | <0.05c |
| Fontan pressure, mm Hg | 15 (13.5–18.5) | 17 (16–20) | 0.211 |
| PVRi, WU × m2 | 1.99 (1.2–2.4) | 3 (1.9–4) | 0.046c |
| Cardiac index, liters/min/m2 | 2.5 (2.2–4.2) | 2.37 (2.28–3.22) | 1 |
| Ischemic time, min | 270 (217–302) | 210 (165–276) | 0.21 |
| Pre-sensitized (PRA > 10%) | 4 (31) | 3 (43) | 0.651 |
PRA, panel reactive antibody; PVRi: indexed pulmonary vascular resistance; WU, Woods units.
a
Cirrhotic Fontan heart transplant patients were significantly older, further from time of Fontan, and had a higher PVRi at listing.
b
Categoric data are shown as number (%) and continuous data as mean ± standard deviation or median (interquartile range).
c
Statistically significant (p < 0.05).