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. 2014 Jan 25;42(7):4652–4668. doi: 10.1093/nar/gkt1416

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© The Author(s) 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — ZC3H11 activity requires the interactions with MKT1 and PBP1. The diagrams on the left illustrate selected mutant versions of ZC3H11. Zn: zinc finger; PY: HNPY motif; S: serine-rich domain. Properties of the mutants are shown in the columns. Only selected, critical, mutants are shown. Bind RNA: ability to bind (UAU) repeats (26). Y2H MKT1: binding to MKT1 in the yeast two-hybrid assay. Y2H PBP1: binding to PBP1 in the yeast two-hybrid assay; Tether effect: ability to increase CAT activity and CAT mRNA in the tethering assay. + , positive result; –, negative result; gap, not done.