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. 2014 Jan 31;42(7):4208–4219. doi: 10.1093/nar/gku102

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© The Author(s) 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — The yeast module map. Each node is a module in the yeast PPI network. The name of a node is the most significantly enriched GO term for that module. Each edge represents a highly significant link between two modules in the negative GI network (P < 1E-50). Modules that were not enriched for any GO term at 0.05 FDR are not shown. Three main chromatin-related hubs are marked in green. Some links connect disjoint modules enriched with similar GO terms (e.g. proteasome–proteasome link, top right), and other links show epistasis between different biological processes (e.g. nuclear pore and ribosome biogenesis, top right).