Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jan 31;42(7):4208–4219. doi: 10.1093/nar/gku102

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — A module map of DNA damage-specific positive GIs. (A) A module map of the significantly enriched modules. Nodes represent modules and edges represent significant links (Bonferonni corrected P < 0.05). The name of a node is the most significantly enriched GO term. (B) A closer look at the DNA repair module and three-linked modules. Nodes represent genes and edges represent interactions: blue—DNA damage-specific positive GIs, pink—PPIs, black—stable positive GIs, which are observed both in the untreated and in the treated cells. This map shows the emerging connections between functional modules on DNA damage response covering DNA repair and checkpoint responses in the DNA repair module, response to damaged replication forks (the DNA damage response module), DNA double-stranded response genes (RAD52 module) and RNA degradation-related genes (SKI complex module). The RAD52 and SKI modules do not appear in A, as they reflect functions that do not have established GO terms.