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SEC analyses of (a) 100 μM β2m incubated with 150 μM Cu(II) (black), 150 μM Zn(II) (blue), and both 150 μM Cu(II) and 150 μM Zn(II) (red) and (b) 100 μM β2m incubated with 150 μM Zn(II) without (black) and with (red) 200 μM Ni(II) or (blue) with 3 mM Ni(II) in 500 mM urea, 150 mM potassium acetate, and 25 mM MOPS (pH 7.4) at 37 °C for 4 days.
