Table 1.

(A) residue categories of 20 canonical amino acids		(B) hydration properties of three optimization cases
amino acids	hydration	notation	case 1	case 2	case 3
Leu, Val, Ile, Met, Phe, Tyr, Trp	hydrophobic	Npho	4	5	3
Glu, Asp	negatively	Nneg	0	0	0
Arg, Lys	positively	Npos	2	2	1
Ser, Thr, Asn, Gln, His	hydrophilic	Npol	5	6	6
Ala, Cys	other	Noth	2	1	3
Gly	neutral	Ngly	2	1	2