Table 1.

Asian cases of BHD except Kunogi et al. [2] and Furuya and Nakatani [3]

Case	Year	First author	Age, years	Gender Skin histology	PC	Family history	RC	Mutation
1	1990	Ishiko [16]	46	M	ff, td, ac	–	–	–	UK
2	2000	Aoki [6]	65	M	ff, td	–	+s	–	UK
3	2001	Takahashi [17]	53	F	ff	–	+ff	+	UK
4	2003	Ishihara [18]	52	F	ff, td, ac	–	+s		UK
5	2004	Kawasaki [7]	26	M	ff	–	+s	–	E11
6			UK	M	NT	–	fath. of 5	–	E11
7	2005	Nagashima [19]	51	F	NF	–	–	+	NF
8	2007	Murakami T [14]	55	UK	NF	–	–	+	E11
9	2007	Gunji [11]	30	F	NF	+	+p	–	E13
10			38	F	NF	+	+p	–	E11
11			40	F	NF	+	+p, r	–	E6
12			37	F	NF	+	+p, r	–	I5
13			38	F	NF	+	+p, r	–	E12
14	2007	Saito [20]	35 (Ch)	M	pff	–	–	–	UK
15	2008	Sadamasa [21]	35	M	ff, td	+	+s	–	UK
16	2008	Misago [22]	67	F	ff, td	–	+s	–	E13
17			38	F	not ff, td	+	dau. of 16	–	E13
18			35	F	not ff, td	+	dau. of 16	–	E13
19	2008	Kim [23]	31 (Ko)	F	pff, td	+	+p	–	E14
20	2009	Imada [8]	68	M	ff	–	+s, r	+	E12
21	2009	Miyasaka [24]	34	F	trunk, NT	+	+p	–	E12
22	2009	Ando [25]	58	F	ff, ac?	+	+p	–	E12
23	2009	Ishii [26]	29	F	NF	+	+p	–	UK
24			40	M	NF	+	bro. of 23	–	E6
25			72	M	NF	+	fath. of 23	–	UK
26	2009	Koga [27]	41	F	NF	+	+ff	–	E12
27			UK	M	ff	–	fath. of 26	–	E12
28	2009	So [28]	57 (Ch)	F	ff	+	+ p	–	E13?
29			31	F	NF	+	dau. of 28	–	E13?
30			28	F	NF	+	dau. of 28	–	E13?
31	2010	Hayashi [29]	39	F	NF	+	–	–	E13
32	2011	Nakagawa [30]	30’	F	NF	+	+p, r	–	E12
33			30’	M	NF	+	bro. of 32	–	UK
34	2011	Sakairi [31]	41	F	NF	+	+ff	–	E12
35			55	F	NF	+	+p	–	E12
36	2011	Park [9]	43 (Ko)	M	ff, td	–	+s, p	–	E11
37	2011	Shin [10]	46 (Ko)	F	NF	+	dau. of 37	+	E5
38			69	F	NF	+	+p, r	+	E5
39	2012	Nagashima [32]	69	F	NF	+	–	+	E5
40	2012	Ishizuka [33]	45	F	NT	+	+p	–	E11
41	2012	Kim [12]	40 (Ko)	F	not ff	+	+p, r	–	E6
42			UK	M	UK	+	fath. of 41	+	UK
43			UK	F	NF	+	sis. of 41	–	E6
44			UK	F	NF	+	sis. of 41	–	E6
45	2012	Kashiwada [34]	60	F	NT?	+	+s, p	–	E11
46			32	M	NT?	+	son of 39	–	E11?
47	2012	Tobino [35]	43	F	NF	+	+p	+*	E12
48			UK	M	NF	+	son of 47	–	UK
49	2013	Ema [36]	53	F	not ff	+	–	+	E6
50	2013	Nishii [13]	33	F	not ff	+	+s, p	–	I5
51			UK	M	extrm., NT	+	fath. of 50	–	I5?
52			UK	M	UK	+	uncle of 50	–	UK
53			UK	F	UK	+	G.M. of 50	–	UK
54	2013	Haga [37]	61	F	NF	+	+p	–	E11
55			29	M	NF	+	son of 54	–	E11
56			UK	M	NF	+	bro. of 54	–	UK
57	This report	Murakami Y	37	F	ff	+	NF	+	UK
58			35	M	ff	+	+p	+	UK
59			UK	F	UK	+	moth. of 58	–	UK
60			UK	F	UK	+	aunt of 58	–	UK
61			UK	M	UK	+	uncle of 58	–	UK
62			UK	M	UK	+	G.F. of 58	–	UK

Ch = Chinese; Ko = Korean; UK = unknown; ff = fibrofolliculoma; td = trichodiscoma; ac = acrochordon; NF = no cutaneous change could be found; NT = not tested; extrm. = extremity; s = skin lesion; p = pulmonary lesion; r = renal lesion; dau. = daughter; sis. = sister; bro. = brother; fath. = father; G.M. = grandmother; moth. = mother; G.F. = grandfather; E = exon; I = intron.

# Diagnosed as renal cyst by abdominal sonography without pathological examination.

^*Diagnosed as angiomyolipoma by CT images without pathological examination.