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. 2014 Mar 19;144(5):784–790. doi: 10.3945/jn.113.189738

FIGURE 1.

FIGURE 1

Stability of biomarkers in EDTA blood stored in a Styrofoam container with an icepack for 24 or 48 h. Biomarkers (pyridoxal, choline, total homocysteine, Arg, and hydroxyanthranilic acid) that changed substantially over time (left panel) had a low intraclass correlation coefficient (<0.2) across the storage time (middle panel), but for some (choline and total homocysteine), concentrations at 24 or 48 h still showed a fair-to-good (ρ > 0.4) correlation with values at time 0 (right panel). This reflects a parallel increase in concentrations over time and implies that the ranking of the values at fixed time points was maintained. ADMA decreased moderately during storage, but both intraclass correlation coefficient and ranking were low, which is explained by the low between-person variability for ADMA. n = 12. ADMA, asymmetric dimethylarginine; FMN, flavin mononucleotide; SDMA, symmetric dimethylarginine.