(A, B) Models
of the complex between JAZ ZF3 and the minimal dsRNA
VAIminMut shown (A) superimposed on the structured portions of the
backbone of ZF3 and (B) superimposed on the backbone of the dsRNA
duplex. (C) Model of the complex between ZF3 and the minimal dsRNA
showing interactions between the side chains of Q202, K207, K208,
K211, and Q212 (shown in red) with the phosphate backbone of the RNA.
The backbone amide of K207 (blue sphere) and the phosphorus of Cyt13
(black) are shown in close proximity in the complex. (D) Single HADDOCK
model with the dsRNA shown in a surface representation, illustrating
the docking of the JAZ ZF3 in the major groove. Figure made with (A,
B, D) PyMol and (C) Molmol.57