Skip to main content
. 2014 Feb 6;136(8):3016–3019. doi: 10.1021/ja4129394

Table 2. Synthesis of ProPhenol Ligands Bearing trans 2,5-Disubstituted Pyrrolidines.

graphic file with name ja-2013-129394_0006.jpg

Ar dra % yieldb % yield (2 steps)b % yieldb
phenyl >19:1 99 (9) 87 (13) 99 (L6)
1-naphthyl 12:1 90 (10) 87 (14) 95 (L7)
2-naphthyl >19:1 61 (11) 41 (15) 84 (L8)
4-biphenyl >19:1 20 (12) 77 (16) 80 (L9)
a

Determined by analysis of the 1H NMR spectrum of the crude material.

b

Isolated yield.