Figure 2.

Characterization of CPP-ELP_BC nanopeptifiers by temperature-regulated turbidimetry. A moderate increase in optical density (OD < 0.1) of solutions at 15 μM is suggestive of self-assembly of ELP_BC unimers into spherical micelles between 38 and 41 °C. A drastic increase in optical density indicates coacervation of CPP-ELP_BCs into micrometer size aggregates between approximately 54 and 66 °C. Arg₅- and Arg₈-ELP_BCs are shown here as representative examples of the thermal behavior of the CPP-ELP_BC library, demonstrating that CPP-functionalization does not perturb the CMT, as compared to the nonfunctionalized ELP_BC control, but does influence the temperature at which aggregation of the micelles occurs.