Table 2. Nanopeptifier Figures-of-Merit Quantified by Flow Cytometry.
nanopeptifier | CPP functionalization | leakage uptakea | amplified uptakea | gainb |
---|---|---|---|---|
Arg5-ELPBC | RRRRR | 2.5 | 12.5 | 5.0 |
Arg8-ELPBC | RRRRRRRR | 11.0 | 129.4 | 11.8 |
TAT-ELPBC | YGRKKRRQRRR | 10.0 | 101.9 | 10.2 |
RTAT-ELPBC | YGRGGRRGRRR | 2.9 | 23.0 | 7.9 |
ELPBC | none | 1.0 | 0.9 | 0.9 |
Measured in arbitrary units of cellular fluorescence, normalized to leakage uptake of nonfunctionalized ELPBC.
Defined as the ratio of amplified to leakage uptake.