Table 5: Modifications to initial targets for vasopressor titration.

Variable	All sites
No. of patients	369
Total no. of targets analyzed	604
Patients with ≥1 explicit target, % (no.) [95% CI]	99 (365) [98 to 100]
Target modifications
Patients with no modifications (only 1 target), % (no.)	54 (199)
Patients with ≥ 1 modification of initial target, % (no.)	40 (148)
Direction of target modifications
Proportion of target changes in the same category that represent an increase in the target value, % (no.)*	41 (33) n = 80
SAP to SAP increase, mm Hg, median (IQR)	+10 (10 to 10)
MAP to MAP increase, mm Hg, median (IQR)	+5 (5 to 5)
Proportion of target changes in the same category that represent a decrement in the target value, % (no.)*	59 (47) n = 80
SAP to SAP decrease, mm Hg, median (IQR)	–10 (–15 to –7.5)
MAP to MAP decrease, mm Hg, median (IQR)	–5 (–5 to –5)

Note: CI = confidence interval, IQR = interquartile range, MAP = mean arterial pressure, SAP = systolic arterial pressure.
*Denominator is no. of patients who had new targets of the same blood pressure variable.