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. 2013 Oct 22;1(4):E127–E133. doi: 10.9778/cmajo.20130006

Table 6: Multivariable logistical model of modifications to blood pressure targets for vasopressor titration during the first 48 hours of intensive care unit stay (n = 277).

Variable OR (95% CI)

SAP or MAP increased (n = 33) v. no change (n = 197)
Centre 1 v. 3
0.79
(0.30 to 2.04)
Centre 2 v. 3
0.34
(0.1 to 1.12)
Acute renal failure v. no acute renal failure
1.46
(0.65 to 3.29)
Myocardial infarction v. no myocardial infarction
1.06
(0.43 to 2.65)
Lactic acid ≥ 4 v. < 4 mmol/L
0.75
(0.32 to 1.79)
Cardiac arrhythmia v. no arrhythmia
0.96
(0.39 to 2.38)

SAP or MAP decreased (n = 47) v. no change (n = 197)
Centre 1 v. 3
0.95
(0.42 to 2.15)
Centre 2 v. 3
0.55
(0.20 to 1.51)
Acute renal failure v. no acute renal failure
1.19
(0.60 to 2.39)
Myocardial infarction v. no myocardial infarction
0.68
(0.30 to 1.53)
Lactic acid ≥ 4 v. < 4 mmol/L
1.44
(0.72 to 2.89)
Cardiac arrhythmia v. no arrhythmia 1.15 (0.54 to 2.44)

Note: CI = confidence interval, MAP = mean arterial pressure, OR = odds ratio, SAP = systolic arterial pressure.