Table 3: Multivariable Cox model for breast cancer–specific survival and overall survival.
Variable | Breast cancer–specific survival |
Overall survival |
||
---|---|---|---|---|
Hazard ratio (95% CI) | Hazard ratio (95% CI) | |||
Age, per yr |
1.02 |
(1.00–1.03) |
1.06 |
(1.05–1.07) |
Grade |
||||
2 v. 1 |
2.0 |
(1.3–2.9) |
1.3 |
(1.0–1.6) |
3 v. 1 |
3.5 |
(2.3–5.2) |
1.9 |
(1.5–2.4) |
LVI, positive v. negative |
1.6 |
(1.2–2.0) |
1.5 |
(1.2–1.8) |
Stage |
||||
II v. I |
3.0 |
(2.2–4.3) |
1.5 |
(1.2–1.8) |
III v. I |
9.8 |
(6.5–14.7) |
4.0 |
(3.1–5.2) |
IV v. I |
47.0 |
(30.6–73.1) |
15.5 |
(11.0–22.0) |
Radiotherapy* |
0.76 |
(0.60–0.96) |
0.68 |
(0.60–0.80) |
Chemotherapy* |
0.58 |
(0.43–0.78) |
NA |
NA |
Hormone therapy* | 0.74 | (0.59–0.95) | 0.70 | (0.59–0.83) |
Note: CI = confidence interval, LVI = lymphatic vascular space invasion, NA = not applicable. *Within 1 year of diagnosis, expressed as the hazard ratio of having had treatment v. not having had treatment.