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. 2013 Nov 7;1(4):E134–E141. doi: 10.9778/cmajo.20130017

Table 3: Multivariable Cox model for breast cancer–specific survival and overall survival.

Variable Breast cancer–specific survival
Overall survival
Hazard ratio (95% CI) Hazard ratio (95% CI)
Age, per yr
1.02
(1.00–1.03)
1.06
(1.05–1.07)
Grade




   2 v. 1
2.0
(1.3–2.9)
1.3
(1.0–1.6)
   3 v. 1
3.5
(2.3–5.2)
1.9
(1.5–2.4)
LVI, positive v. negative
1.6
(1.2–2.0)
1.5
(1.2–1.8)
Stage




   II v. I
3.0
(2.2–4.3)
1.5
(1.2–1.8)
   III v. I
9.8
(6.5–14.7)
4.0
(3.1–5.2)
   IV v. I
47.0
(30.6–73.1)
15.5
(11.0–22.0)
Radiotherapy*
0.76
(0.60–0.96)
0.68
(0.60–0.80)
Chemotherapy*
0.58
(0.43–0.78)
NA
NA
Hormone therapy* 0.74 (0.59–0.95) 0.70 (0.59–0.83)

Note: CI = confidence interval, LVI = lymphatic vascular space invasion, NA = not applicable.
*Within 1 year of diagnosis, expressed as the hazard ratio of having had treatment v. not having had treatment.