Table 3. Multivariable analysis of mortality predictors in Beijing and Boston cohorts.
| Beijing cohort | Boston cohort | ||||
| Covariate | AHR (95% CI) | p | AHR (95% CI) | p | |
| ARDS | N = 75 | N = 851 | |||
| APACHE II | 1.05 (1.00–1.10) | 0.04 | 1.05 (1.03–1.08) | <0.0001 | |
| Thrombocytopenia | 2.20 (1.09–4.46) | 0.03 | 1.69 (1.23–2.32) | 0.001 | |
| Age | NS | 1.03 (1.02–1.04) | <0.0001 | ||
| Bilirubin, >2.0 mg/dL | NS | 1.45 (1.08–1.95) | 0.01 | ||
| Non-ARDS | N = 103 | N = 1027 | |||
| APACHE II | 1.08 (1.04–1.12) | 0.0002 | 1.07 (1.04–1.10) | <0.0001 | |
| Thrombocytopenia | 1.29 (0.64–2.59) | 0.48 | 1.63 (1.14–2.34) | 0.008 | |
| Pneumonia | 2.04 (1.02–4.09) | 0.04 | NS | ||
| Age | NS | 1.03 (1.02–1.04) | <0.0001 | ||
| Aspiration | NS | 1.79 (1.18–2.73) | 0.006 | ||
| All patients | N = 178 | N = 1878 | |||
| APACHE II | 1.07 (1.03–1.10) | <0.0001 | 1.07 (1.05–1.08) | <0.0001 | |
| Thrombocytopenia | 1.89 (1.16–3.08) | 0.01 | 1.97 (1.56–2.48) | <0.0001 | |
| Pneumonia | 2.01 (1.24–3.26) | 0.005 | NS | ||
| Age | NS | 1.02 (1.02–1.03) | <0.0001 | ||
| Trauma | NS | 0.09 (0.01–0.67) | 0.02 | ||
| Direct pulmonary injury | NS | 1.36 (1.12–1.65) | 0.002 | ||
ARDS = acute respiratory distress syndrome; APACHE = Acute Physiology and Chronic Health Evaluation; AHR = adjusted hazard ratio; CI = confidence intervals; NS = not selected in multivariate modeling.