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. 2014 Apr 14;9(4):e94124. doi: 10.1371/journal.pone.0094124

Table 4. Sensitivity analysis of combined effects of thrombocytopenia and ARDS.

cutoff point for platelet count* Platelet count <cutoff & Non-ARDS Platelet count ≥cutoff & ARDS Platelet count <cutoff & ARDS
AHR p AHR p AHR p
50 1.39(0.81,2.36) 0.2286 1.79(1.47,2.18) 6.50E-09 3.62(2.45,5.34) 8.80E-11
60 1.36(0.84,2.19) 0.2107 1.74(1.42,2.13) 6.30E-08 3.91(2.78,5.51) 5.40E-15
70 1.37(0.90,2.07) 0.1407 1.76(1.43,2.15) 5.60E-08 3.43(2.47,4.76) 1.80E-13
80 1.51(1.04,2.19) 0.0308 1.75(1.42,2.16) 1.50E-07 3.40(2.51,4.60) 2.10E-15
90 1.44(1.01,2.05) 0.0459 1.68(1.36,2.08) 1.90E-06 3.66(2.74,4.87) <1E-16
100 1.42(1.02,1.97) 0.0356 1.68(1.35,2.09) 3.00E-06 3.47(2.62,4.59) <1E-16
110 1.35(0.99,1.85) 0.0587 1.68(1.34,2.09) 5.20E-06 3.19(2.42,4.19) 1.10E-16
120 1.39(1.03,1.88) 0.0316 1.69(1.35,2.12) 5.00E-06 3.12(2.38,4.09) 2.20E-16
130 1.33(0.99,1.77) 0.0543 1.70(1.35,2.15) 7.20E-06 2.84(2.18,3.69) 1.20E-14
140 1.25(0.94,1.65) 0.1213 1.73(1.36,2.19) 5.80E-06 2.58(1.99,3.36) 1.60E-12
150 1.27(0.97,1.67) 0.0856 1.73(1.36,2.21) 1.00E-05 2.58(1.99,3.34) 8.80E-13

ARDS = acute respiratory distress syndrome; AHR = adjusted hazard ratio.

*Each line represents a multivariate cox regression with adjustment of age, gender, APACHII score, and sepsis; Platelet count (×103/µL) was dichotomized by cutoff point;

AHR was estimated by comparison with non-thrombocytopenia/non-ARDS group.