Table 4. Sensitivity analysis of combined effects of thrombocytopenia and ARDS†.
cutoff point for platelet count* | Platelet count <cutoff & Non-ARDS | Platelet count ≥cutoff & ARDS | Platelet count <cutoff & ARDS | |||
AHR† | p | AHR† | p | AHR† | p | |
50 | 1.39(0.81,2.36) | 0.2286 | 1.79(1.47,2.18) | 6.50E-09 | 3.62(2.45,5.34) | 8.80E-11 |
60 | 1.36(0.84,2.19) | 0.2107 | 1.74(1.42,2.13) | 6.30E-08 | 3.91(2.78,5.51) | 5.40E-15 |
70 | 1.37(0.90,2.07) | 0.1407 | 1.76(1.43,2.15) | 5.60E-08 | 3.43(2.47,4.76) | 1.80E-13 |
80 | 1.51(1.04,2.19) | 0.0308 | 1.75(1.42,2.16) | 1.50E-07 | 3.40(2.51,4.60) | 2.10E-15 |
90 | 1.44(1.01,2.05) | 0.0459 | 1.68(1.36,2.08) | 1.90E-06 | 3.66(2.74,4.87) | <1E-16 |
100 | 1.42(1.02,1.97) | 0.0356 | 1.68(1.35,2.09) | 3.00E-06 | 3.47(2.62,4.59) | <1E-16 |
110 | 1.35(0.99,1.85) | 0.0587 | 1.68(1.34,2.09) | 5.20E-06 | 3.19(2.42,4.19) | 1.10E-16 |
120 | 1.39(1.03,1.88) | 0.0316 | 1.69(1.35,2.12) | 5.00E-06 | 3.12(2.38,4.09) | 2.20E-16 |
130 | 1.33(0.99,1.77) | 0.0543 | 1.70(1.35,2.15) | 7.20E-06 | 2.84(2.18,3.69) | 1.20E-14 |
140 | 1.25(0.94,1.65) | 0.1213 | 1.73(1.36,2.19) | 5.80E-06 | 2.58(1.99,3.36) | 1.60E-12 |
150 | 1.27(0.97,1.67) | 0.0856 | 1.73(1.36,2.21) | 1.00E-05 | 2.58(1.99,3.34) | 8.80E-13 |
ARDS = acute respiratory distress syndrome; AHR = adjusted hazard ratio.
*Each line represents a multivariate cox regression with adjustment of age, gender, APACHII score, and sepsis; Platelet count (×103/µL) was dichotomized by cutoff point;
AHR was estimated by comparison with non-thrombocytopenia/non-ARDS group.