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. 2014 Apr 14;9(4):e91992. doi: 10.1371/journal.pone.0091992

Figure 8. Dynamics of the Shannon diversity index, Inline graphic, of individual tumors evolving in angiogenic commitment (Inline graphic) for two different constant proliferation commitments: (A) Inline graphic min−1; (B) Inline graphic min−1.

Figure 8

Purple curves in both panels represent the first 20 of the 1000 simulations plotted in Fig. 5. Solid black curves are the ensemble averages of all 1000 runs. Dashed red lines represent mean time of the final mutation (Inline graphic), with Inline graphic.