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. 2014 Apr 14;9(4):e94468. doi: 10.1371/journal.pone.0094468

Figure 4. The disruption of SPT20 affected C. albicans stress responses and antifungal susceptibility.

Figure 4

Ten-fold serial dilutions of the wild-type, spt20Δ/Δ, and spt20/SPT20 were evaluated for susceptibility to cell wall stressors and antifungal agents. The spt20Δ/Δ mutant was specifically susceptible to SDS and NaCl at all the temperatures tested, 25°C (A), 30°C (B) and 37°C(C). The spt20Δ/Δ mutant was hypersensitive to amphotericin B, fluconazole and caspofungin, but was not sensitive to 5-fluorocytosine (D).