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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Neurotoxicology. 2014 Jan 21;41:54–63. doi: 10.1016/j.neuro.2014.01.002

Figure 2. Effect of stretch on SH-SY5Y cell survival/death in the presence of paraquat (PQ).

Figure 2

Cells were stretched at the indicated strain levels 2 h before exposure to paraquat. Cell death was evaluated 48 h after paraquat treatment by PI uptake and cell survival was analyzed by MTT. (A) Representative histograms of changes in PI fluorescence (loss of plasma membrane integrity is reflected as an increase in PI fluorescence). (B) PI uptake results are represented as the increase in mean PI fluorescence with respect to controls. (C) Cell viability of SH-SY5Y cells was determined by MTT. Data represent the mean ± SEM of five independent experiments (n=5). *P< 0.05 and **P< 0.01.