Table 2.
Baseline characteristics of PCLD-1 family
| Characteristics | No hepatic cystogenesis and no LRP5 mutation (n = 9) | Hepatic cystogenesis and LRP5 mutation (n = 13) | P value |
| Age (y) | 55 ± 12 | 56 ± 13 | NS |
| Female sex, no. (%) | 6 (67) | 9 (69) | NS |
| Bone density: Hip | |||
| T-score | −0.19 ± 0.78 | −0.08 ± 0.93 | NS |
| Z-score | 0.69 ± 0.68* | 0.95 ± 0.94 | NS |
| Bone density: L1-L2-L3-L4 | |||
| T-score | 1.18 ± 0.95* | 0.19 ± 0.88 | 0.042 |
| Z-score | 1.81 ± 0.89* | 1.18 ± 1.03 | NS |
| Creatinin (µmol/L) | 69 ± 14 | 73 ± 20 | NS |
| Cholesterol (mmol/L) | 5.39 ± 0.71 | 5.44 ± 1.01 | NS |
| GFR (MDRD) (ml/min/1.73 m2) | 87 ± 13 | 85 ± 25 | NS |
| BMI (kg/m2) | 25.7 ± 2.5 | 26.4 ± 5.2 | NS |
| Triglycerides (mmol/L) | 1.35 ± 0.71 | 1.80 ± 0.93 | NS |
| HDL (mmol/L) | 1.34 ± 0.40 | 1.38 ± 0.32 | NS |
| LDL (mmol/L) | 3.44 ± 0.82 | 3.25 ± 0.78 | NS |
| Non HDL (mmol/L) | 4.06 ± 0.93 | 4.07 ± 0.93 | NS |
| HbA1C (%) | 5.5 ± 0.6 | 5.7 ± 0.8 | NS |
| HbA1C (mmol/mol) | 37 ± 6 | 39 ± 9 | NS |
NS, not significant.
*
There was one missing value because of degenerative abnormalities of the lumbar spine in an 85-y-old woman.