Fig. 2.

(A) Bilateral regions of the primary motor cortex showed increased levels of drinking-related activation during the overdrinking condition compared with the thirst condition. (B) BOLD signals measured from an activated cluster in the right motor cortex (indicated by white arrow in A) show hemodynamic responses associated with drinking during the thirst condition (closed blue squares) and during the overdrinking condition (open red triangles). Drinking events were averaged according to the timing of water placed in the mouth (time = 0 s). The signal increases associated with drinking were larger during the overdrinking condition compared with the thirst condition. *P < 0.05.