Fig. 5.

Refined model membrane domains. Refined models of E₂P and E₂ states are shown in cartoon with helices M1–M2 in purple, M3–M4 in green, M5–M6 in ochre, and M7–M10 as silver molecular isosurface representation. Partial A- and P-domains are shown in yellow and blue, respectively. Unrefined models are shown as transparent gray cartoons. The models were aligned using M7–M10 helix backbones as reference. Black lines denote membrane borders, defined as average phospholipid head group-phosphate positions.