Fig. 2.

Protein lateral mobility in fluctuating membranes. Semilogarithmic plot of the diffusion coefficients (D_eff) as a function of the membrane tension Σ, for AQP0 and KvAP labeled with streptavidin QDs. Each point represents a median diffusion coefficient obtained from hundreds of individual trajectories for a GUV at a given tension; the error bars correspond to SE. KvAP data adjusted by Eq. 3 (solid line) yields a protein coupling coefficient considering , and . Simulations of the protein diffusion on a membrane subject to thermal fluctuations agree well with the experimental data and theory. (Insets) Sketches of membrane deformation near proteins.