Table 2.
Model parameters
| Description | Value | Distribution | Source/Remarks |
| p, proportion cured by preventive therapy | 0–1 | — | Estimated by fitting |
| λ, annual risk of M. tuberculosis infection | 0+ | — | Estimated by fitting |
| dRi=1, risk of disease in first year following reinfection, per year | 5% | Normal (mean = 5, 95%, CI = 1–10) | (10,11) |
| dRi=2, risk of disease in second year following reinfection, per year | 0.41 × dRi=1 | — | (10) |
| dL, risk of disease due to reactivation in Latent stage, per year | 0.13 × dRi=1 | — | (10) |
| RRR, relative risk of disease following recent reinfection in HIV+ vs. HIV−, per year | — | — | Depends on CD4 (SI Appendix) |
| µ, ratio RRR:RRL | 3:1 | Normal (mean = 3, 95%, CI = 1–5) | (14) |
| RRL, relative risk of disease following reactivation in HIV+ vs. HIV−, per year | — | — | = RRR / µ |
CI, confidence interval.