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. 2014 Apr 14;9(4):e94443. doi: 10.1371/journal.pone.0094443

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© 2014 Yang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Morphology of PBT003, PBT008, PBT022 and PBT030 neurospheres in stem cell culture medium. (B) GBM neurospheres expressed specific biomarkers for normal neural stem cells. (C) GBM neurospheres exhibit the ability to differentiate.