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. 2014 Apr 14;9(4):e94443. doi: 10.1371/journal.pone.0094443

Figure 6. Western blotting analysis of BBMD3 induced phosphorylation of JNK 1 and 2, c-Jun and total c-Fos protein expression in cells derived from human GBM neurospheres.

Figure 6

(A) The effect of BBMD3 on the expression of total and phosphorylated STAT3 in cells derived from PBT003, PBT008, PBT022 and PBT030 neurospheres following a 24 hour treatment with BBMD3. (B) Western Blotting analysis of cell lysates probing for phosphorylated JNK expression following a 24 hour treatment of cells derived from GBM neurospheres with BBMD3. (C) Phosphorylation of c-Jun and quantification of c-Fos total protein expression following BBMD3 treatment.