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. 2014 Apr 14;9(4):e94618. doi: 10.1371/journal.pone.0094618

Table 1. Demographic, clinical and laboratory results of MDR suspects (n = 9).

Status Age Sexe Clinical History N° of FLD course Culture and DST on LJ in NRL Kinshasa RpoB Sequencing at SRL in Antwerp Treatment outcomes of SLD assessed in 2011
SM Culture ID RMP INH
A Case 20 F F2 3 + + MTBC R C His526Tyr(TAC) Treatment completed
B Case 29 M F1 2 ++ + MTBC R R Ser531Trp(TGG) Died
C Case 31 F R2 3 ++ + MTBC R R Ser531Leu(TTG), Arg633Leu (CTC) Cured
D Case 38 M F2 3 ++ + MTBC S R His526Leu(CTC) Died
A1 Contact 6 F NA NA 0 NG NT
A2 Contact 22 M NA NA 0 NG NT
B1 Contact 59 F NA NA 0 NG NT
C1 Contact 24 F NA NA 0 NG NT
D1 Contact 41 M NA NA 0 NG NT

A1: First contact of case A; A2: Second contact of case A; B1: First contact of case B; C1: First contact of case C; D1: First contact of case D. M: male; F: female. F1: Failure in WHO standard first line treatment regimen for category 1 for new cases; F2: Failure in WHO standard first line treatment regimen for category 2 retreatment cases; R2: Relapse in WHO standard first line treatment regimen for category 2 retreatment cases. NA: Not applicable. N° of FLD: Number of first-line drugs. SM: smear microscopy results. NG: no growth. ID: identification. MTBC: Mycobacterium tuberculosis complex. NT: not tested. R: Resistant; S: sensitive; C: contaminated. SLD: second-line drugs.