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(A) NE perfused for 3 min significantly depolarized the resting membrane potentials. *p<0.05 vs. Pre-NE group. (B) NE application markedly reduced rheobase. *p<0.05 vs. Pre-NE group. (C, D) Representative traces of action potentials (APs) induced by 2 and 3 times rheobase current injection. Bar graph showed a significant increase in number of APs after NE application, *p<0.05 vs. pre-NE group.
