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. 2014 Apr 14;9(4):e94802. doi: 10.1371/journal.pone.0094802

Table 3. Significantly associated SNPs for birth weight (BW), weaning weight (WW), and long-yearling weight (LYW) obtained by the Generalized Quasi-Likelihood Score method (GQLS).

Trait SNP Reference BTA Position (bp) Alleles Genes Region MAF p-value FDR Allele substitution effect*
BW rs43421095 4 117,400,491 A,C DPP6 Intron 0.2957 1.39E-06 5% −0.5929
BW rs135754703 9 55,075,535 A,C LOC783932, MANEA Intergenic 0.4552 8.22E-06 10% −0.41612
BW rs136146400 9 55,078,557 A,G LOC783932, MANEA Intergenic 0.4563 7.23E-06 10% −0.41976
BW rs109313268 9 55,103,057 T,C LOC783932, MANEA Intergenic 0.4962 3.98E-06 10% −0.44946
WW rs43421095 4 117,400,491 A,C DPP6 Intron 0.2957 1.91E-07 1% −2.84898
WW rs135156506 6 35,008,291 T,C FARSB Upstream 0.1582 7.32E-07 5% −2.17934
WW rs135591504 6 41,978,318 T,C KCNIP4 Intron 0.2273 2.74E-06 5% 1.55340
WW rs136337296 11 103,096,174 T,C GTF3C5 Intron 0.365 1.81E-05 10% 1.82227
WW rs109348820 11 103,154,983 T,C RALGDS Intron 0.3916 2.02E-05 10% 1.76133
WW rs133132366 11 103,157,389 T,C RALGDS Intron 0.4077 1.28E-05 10% 1.81074
WW rs134657108 11 103,162,503 A,G RALGDS Intron 0.4177 1.26E-05 10% 1.90613
WW rs136054783 11 103,167,055 A,G RALGDS Intron 0.4066 8.40E-06 10% 1.79279
WW rs136961684 11 103,170,500 A,G RALGDS Intron 0.4076 1.08E-05 10% −1.80009
WW rs109945520 11 103,171,584 G,T RALGDS Intron 0.4047 1.17E-05 10% 1.80350
WW rs109524492 11 103,172,572 C,T RALGDS Intron 0.4099 5.74E-06 10% 1.63200
WW rs110048168 11 103,174,303 A,C RALGDS Intron 0.3886 3.05E-06 10% −1.66682
LYW rs29011435 7 28,515,652 T,C MARCH3, LMNB1, PHAX, ALDH7A1, C7H5orf48, GRAMD3, MIR2458, LOC100848523 Intergenic 0.374 4.62E-06 10% 3.59660
LYW rs134201365 7 28,522,539 T,G MARCH3, LMNB1, PHAX, ALDH7A1, C7H5orf48, GRAMD3, MIR2458, LOC100848523 Intergenic 0.375 4.62E-06 10% −3.59660
LYW rs109581958 22 54,624,190 T,C LARS2, LOC101907967, TMEM158, LOC101908013, CDCP1, LOC614114, LOC101908094, LOC101901958, ZDHHC3, EXOSC7, LOC100847326, CLEC3B Intergenic 0.2335 1.09E-05 10% −3.61775
LYW rs110246286 22 54,625,467 T,C LARS2, LOC101907967, TMEM158, LOC101908013, CDCP1, LOC614114, LOC101908094, LOC101901958, ZDHHC3, EXOSC7, LOC100847326, CLEC3B Intergenic 0.2348 1.09E-05 10% −3.61775
LYW rs109242147 25 15,697,543 A,G XYLT1 Intron 0.1192 1.26E-06 5% 3.24823
LYW rs109646351 27 2,614,991 A,G LOC101904868 Intron 0.4456 3.05E-05 10% −3.91546
LYW rs109822265 27 2,619,242 A,C LOC101904868 Intron 0.4454 3.05E-05 10% 3.91546
LYW rs110603636 27 2,620,088 A,C LOC101904868 Intron 0.4456 3.05E-05 10% 3.91546
LYW rs110994026 27 2,620,961 T,C LOC101904868 Intron 0.4494 3.46E-05 10% −3.85715
LYW rs134791735 27 2,623,000 T,G LOC101904868 Intron 0.4443 3.05E-05 10% 3.91546

Single locus regression was carried out to estimate allele substitution effects for significant SNPs.

*Coefficient of regression (P<0.001); FDR  =  False discovery rate; MAF  =  Minor allele frequency; bp  =  base pairs; BTA  =  Bos taurus autosome.