Table 1. Patient characteristics of all intensively treated patients with WBC≥100 G/l.

		n = 52
characteristic	n		%
Age (years)
median		60
range		21–79
Female sex	30		58
ECOG 3/4	37		84
De novo AML	42		81
First diagnosis	43		83
WBC (G/l)
median		159
range		100–322
Platelets (G/l)
median		45
range		10–149
Hemoglobin level (g/dl)
median		9.5
range		5.0–14.9
LDH level (U/l) n = 46
median		996
range		444–7387
BM blasts (%) n = 40
median		87
range		46–99
PB blasts (%) n = 47
median		84
range		14 * –99

Patients with hyperleukocytosis had a reduced ECOG performance status and highly elevated WBC, LDH level and blast counts.

Abbreviations: BM blasts; bone marrow blasts; EOCG, Eastern Cooperative Group; LDH, lactase dehydrogenase; PB blasts; blasts in the peripheral blood; WBC, white blood count.

*one patient with an AML M5A showed 14% of myeloblasts in the peripheral blood, not accounting for the 59% of monoblasts in AML M5.