Table 1.
Demographic and neuropsychological data
| Participant group |
||||||
|---|---|---|---|---|---|---|
| HC n=39 |
CC n=34 |
MCI n=34 |
AD n=13 |
P | Group differencesa | |
| Age (yrs) | 71.8 (5.1) | 74.1 (6.2) | 73.6 (6.1) | 75.2 (7.0) | NS | – |
| Education (yrs) | 16.8 (2.6) | 16.6 (2.8) | 16.6 (2.9) | 14.4 (3.5) | NS | – |
| Gender: M/F | 12/27 | 10/24 | 17/17 | 5/8 | NS | – |
| CCI (%) | 7.2 (5.5) | 23.8 (8.5) | 30.0 (12.1) | 36.7 (10.3) | <.001 | MCI, AD>CC>HC |
| MMSE | 29.0 (1.1) | 28.9 (1.3) | 26.8 (1.5) | 22.4 (3.9) | <.001 | HC, CC>MCI>AD |
| DRS-2 | 141.6 (1.7) | 141.0 (2.1) | 137.7 (3.9) | 123.2 (12.1) | <.001 | HC, CC>MCI>AD |
| CVLT-II | ||||||
| Learning | 50.4 (8.4) | 46.3 (8.4) | 33.9 (6.6) | 24.1 (6.5) | <.001 | HC, CC>MCI>AD |
| Short delay | 11.2 (3.0) | 10.1 (2.8) | 6.1 (2.6) | 1.8 (1.9) | <.001 | HC, CC>MCI>AD |
| Long delay | 11.9 (2.8) | 10.9 (2.7) | 6.2 (3.1) | 0.9 (1.7) | <.001 | HC, CC>MCI>AD |
| TOP-J | 37.4 (3.9) | 33.7 (3.9) | 34.2 (4.4) | 29.6 (5.2) | <.001 | HC>CC, MCI>AD |
Data are Mean (SD) except where otherwise noted.
CCI=Cognitive Complaint Index (Saykin et al. 2006); MMSE=Mini Mental State Exam, raw score (n/30); DRS-2=Mattis Dementia Rating Scale-2, raw score (n/144); CVLT-II=California Verbal Learning Test, Second Edition, total learning score (n/80), short delay free recall score (n/16), and long delay free recall score (n/16); TOP-J=Test of Practical Judgment, total raw score (n/45).
a
Posthoc analyses were conducted using Tukey’s procedure.