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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Biomed Mater Res A. 2013 Aug 10;102(7):2208–2219. doi: 10.1002/jbm.a.34900

Figure 7.

Figure 7

In vivo functional characterization of electrospun dual layer CDVs. Comparison of insulin release and activity in directly implanted insulin pellets (LinBit), and insulin pellets enclosed within a CDV made of electrospun dual layer membranes. A) Random blood sugar level (BSL) measurements illustrating comparable BSL levels of both insulin pellet containing groups.(● – LinBit insulin pellets in CDV pouch N=2); ▼- LinBit insulin pellets implanted alone N=2);. ■ – Akita Diabetic Control; ◆Normal Control.

B) Fasting BSL levels of the same groups illustrating the ability of the CDV electrospun membranes to allow passage of insulin across the barrier. (n = 2 for insulin pellet groups, Fasting BSL at 5 hours at 8 days and at 12 hours for 22 and 27 days).