Table 1. Contrasting phenotypes of the lymphatic endothelial cells and blood endothelial cells in human lymph nodes.
PROX1 | LYVE1 | STAB2 | DCN46 | VEGFR3 | CD144 | CD31 | CD59 | CD105 | |
LECs in subcapsular and trabecular sinuses | + | − | − | − | + v | + | + | − | − |
LECs in paracortical sinuses | + | +/− | +/− | +/− | + v | + | + | − | − |
LECs in medullary sinuses | + | + | + | + | + v | + | + | − | − |
LECs in sinuses surrounding the hilum | + | + | + | + | + v | + | + | − | − |
BECs | − | − | − | − | + v | + | + | + | + |
+: consistent expression by all cells | |||||||||
+ v: varying level of expression by all cells | |||||||||
+/−: majority of cells positive | |||||||||
−: no expression on any cells | |||||||||
LECs: lymphatic endothelial cells | |||||||||
BECs: blood endothelial cells |