Figure 4.

miRNA expression in adipose tissue of 8-week-old male offspring. (A) Expression of 5 candidate miRNAs relative to miR-185 and snRNA U6 housekeepers. (B) IRS-1 protein level and parallel miR-126 expression in adipose tissue from 8-week old male offspring. (C) Seed sequence of miR-126 (red) predicted to target the IRS1 3'-UTR. n=8 per group, Control (white bars) and Mat-Ob (grey bars). ⁎p<0.05 determined by Student's t-test.