Table 2.
Comparison of Hormones and Free Fatty Acid Between the Fermented Red Ginseng (FRG) Group and the Placebo Group
| Markers | Sample | Groups | Mean ± SD (n) | p1) (p2)) | Δ2nd – 1st |
|
|---|---|---|---|---|---|---|
| Mean ± SD (n) | p1) | |||||
| ACTH (pg/mL) | 1st | Placebo | 19.6 ± 10.1 (43) | 0.712 | ||
| FRG | 20.6 ± 13.2 (49) | |||||
| 2nd | Placebo | 20.4 ± 10.1 (44) | 0.321 | 2.3 (43) | 0.52 | |
| FRG | 22.7 ± 11.8 (49) | (0.34) | 0.9 (49) | |||
| Cortisol (μg/dL) | 1st | Placebo | 11.4 ± 3.3 (43) | 0.064 | ||
| FRG | 9.9 ± 4.2 (49) | |||||
| 2nd | Placebo | 11.2 ± 3.5 (44) | 0.531 | −0.2 (43) | 0.13 | |
| FRG | 10.8 ± 3.8 (49) | (0.52) | 0.9 (49) | |||
| Estradiol (pg/mL) | 1st | Placebo | 22.6 ± 17.3 (20) | 0.693 | ||
| FRG | 20.6 ± 15.1 (20) | |||||
| 2nd | Placebo | 14.5 ± 7.3 (19) | 0.083 | −7.4 (19) | 0.06* | |
| FRG | 18.3 ± 7.3 (19) | (0.06*) | 1.0 (19) | |||
| GH (ng/mL) | 1st | Placebo | 1.4 ± 1.3 (20) | 0.424 | ||
| FRG | 1.9 ± 2.6 (20) | |||||
| 2nd | Placebo | 0.9 ± 1.2 (20) | −0.40 (20) | 0.50 | ||
| FRG | 1.8 ± 1.4 (20) | (0.06*) | −0.06 (20) | |||
| DHEAS (μg/dL) | 1st | Placebo | 71.5 ± 28.9 (43) | 0.412 | ||
| FRG | 66.7 ± 26.8 (49) | |||||
| 2nd | Placebo | 65.2 ± 31.4 (44) | 0.871 | −6.2 (43) | 0.03** | |
| FRG | 66.2 ± 29.1(49) | (0.05*) | 0.5 (49) | |||
| Insulin (μU/mL) | 1st | Placebo | 6.5 ± 7.2 (43) | 0.667 | ||
| FRG | 7.1 ± 6.2 (49) | |||||
| 2nd | Placebo | 6.4 ± 3.6 (43) | 0.838 | 1.0 (43) | 0.01** | |
| FRG | 6.3 ± 2.9 (48) | (0.04**) | −0.2 (48) | |||
| Glucose (mg/dL) | 1st | Placebo | 91.9 ± 8.9 (43) | 0.211 | ||
| FRG | 89.9 ± 6.8 (49) | |||||
| 2nd | Placebo | 89.6 ± 6.8 (44) | 0.128 | 2.2 (43) | 0.85 | |
| FRG | 87.4 ± 7.1 (49) | (0.31) | 2.5 (49) | |||
| FSH (mIU/mL) | 1st | Placebo | 73.8 ± 25.6 (20) | 0.261 | ||
| FRG | 65.6 ± 19.6 (20) | |||||
| 2nd | Placebo | 74.0 ± 24.3 (20) | 0.387 | 0.1 (20) | 0.44 | |
| FRG | 68.0 ± 18.5 (20) | (0.68) | 2.4 (20) | |||
| LH (mIU/mL) | 1st | Placebo | 37.8 ± 14.7 (20) | 0.068* | ||
| FRG | 30.6 ± 8.8 (20) | |||||
| 2nd | Placebo | 38.8 ± 14.8 (20) | 0.036** | 1.0 (20) | 0.56 | |
| FRG | 30.3 ± 9.0 (20) | (0.30) | −0.3 (20) | |||
| TSH (μIU/mL) | 1st | Placebo | 2.7 ± 1.6 (20) | 0.058* | ||
| FRG | 1.9 ± 1.0 (20) | |||||
| 2nd | Placebo | 2.8 ± 1.8 (20) | 0.298 | 0.1 (20) | 0.41 | |
| FRG | 2.3 ± 1.2 (20) | (0.80) | 0.4 (20) | |||
| T3 (pg/dL) | 1st | Placebo | — | |||
| FRG | — | |||||
| 2nd | Placebo | 912.1 ± 912 (20) | 0.12 (20) | 0.33 | ||
| FRG | 935.6 ± 123 (20) | (0.86) | 0.06 (20) | |||
| FFA (μEq/L) | 1st | Placebo | 662.4 ± 232.1 (43) | 0.901 | ||
| FRG | 656.8 ± 197.3 (49) | |||||
| 2nd | Placebo | 640.0 ± 223.7 (44) | 0.653 | −23.5 (43) | 0.61 | |
| FRG | 660.3 ± 217.0 (49) | (0.61) | 3.8 (49) | |||
| Brachial Pulse rate (beats/min) | 1st | Placebo | 70.1 ± 8.4 (48) | 0.654 | ||
| FRG | 69.4 ± 9.5 (44) | |||||
| 2nd | Placebo | 68.5 ± 8.5 (48) | 0.957 | −0.6 (47) | 0.494 | |
| FRG | 68.4 ± 8.5 (43) | (0.829) | −1.7 (44) | |||
* p < 0.1.
** p < 0.05.
*** p < 0.01.
Δ2nd – 1st, second sample minus first sample; (n), number of samples; ACTH, adrenocorticotropic hormone; DHEAS, dehydroepiandrosterone; FSH, follicle stimulating hormone; GH, growth hormone; LH, luteinizing hormone; SD, standard deviation; T3, tri-iodothyronine; TSH, thyroid-stimulating hormone.
Independent t test.
Analysis of covariance.