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Transcription of TNFA in THP-1 cells treated with 5-aza-2dC. A) Cells treated with 5-aza-2dC exhibited an increase of TNFA transcription in a time-dependent manner in comparison to mock treated cells (“*” indicates p=0.03 and “**” indicates p=0.003). B) THP-1 cells pretreated with 5-aza-2dC are more responsive to C. rectus challenge by increasing TNFA transcription (p=0.006, as indicated by “*”).
