Table 3.
Potential determinants for breast density and tumour detection
|
Factor |
Category |
Breast density |
|
||
|---|---|---|---|---|---|
| |
|
Fatty (n = 93) |
Moderate (n = 312) |
Dense (n = 214) |
|
| Number (column percent) Mean, SD in italics | p-value** | ||||
| Age at baseline |
Years |
60.1 (7.1) |
56.8 (6.8) |
55.1 (6.7) |
<0.0001 |
| Age at diagnosis |
Years |
67.4 (7.3) |
65.2 (7.1) |
62.0 (7.6) |
< 0.0001 |
| HRT at diagnosis |
No |
25 (26.9) |
126 (40.4) |
46 (21.5) |
<0.0001 |
| |
Yes |
10 (10.8) |
84 (26.9) |
106 (49.5) |
|
| |
Unknown |
58 (62.4) |
102 (32.6) |
62 (29.0) |
|
| Menopausal status at diagnosis |
Premenopausal |
3 (3.2) |
18 (5.8) |
32 (15.0) |
0.001 |
| |
Postmenopausal |
89 (95.7) |
287 (92.0) |
177 (82.7) |
|
| |
Unknown |
1 (1.1) |
7 (2.2) |
5 (2.3) |
|
| BMI at baseline |
<20 |
0 (0.0) |
10 (3.2) |
17 (7.9) |
<0.0001 |
| |
20- < 25 |
29 (31.2) |
135 (43.3) |
129 (60.3) |
|
| |
25- < 30 |
27 (29.0) |
123 (39.4) |
53 (24.8) |
|
| |
≥30 |
37 (39.8) |
44 (14.1) |
15 (7.0) |
|
| Detection mode (three categories) |
Non-symptomatic |
50 (53.8) |
183 (58.7) |
117 (54.7) |
0.333 |
| |
Interval |
10 (10.8) |
43 (13.8) |
34 (15.9) |
|
| |
Symptomatic |
31 (33.3) |
83 (26.6) |
63 (29.4) |
|
| |
Unknown* |
2 (2.2) |
3 (1.0) |
0 (0.0) |
|
| Detection mode (symptomatic including interval cancers) |
Non-symptomatic |
50 (53.8) |
183 (58.7) |
117 (54.7) |
0.559 |
| Symptomatic | 43 (46.2) | 129 (41.3) | 97 (45.3) | ||
*Unknown if interval or symptomatic cancer.
**Continuous variables analysed with ANOVA and categorical variables with the Chi-2 test.