Table 10.

Relationship between APOE ε2 and ε4 and CAA in AD brains

		APOE ε2			APOE ε4
		OR	95% CI (OR)	p	OR	95% CI (OR)	p
All	pCAA	2.60	(1.35-5.03)	0.005**	1.71	(0.90-3.27)	0.102
	mCAA	8.03	(2.77-23.27)	<0.001**	2.14	(1.09-4.21)	0.028*
Frontal	pCAA	2.56	(1.22-5.36)	0.013*	1.44	(0.78-2.67)	0.243
	mCAA	6.03	(2.14-16.96)	0.001***	2.37	(1.21-4.65)	0.012*
Temporal	pCAA	3.80	(1.59-9.08)	0.003**	1.43	(0.73-2.81)	0.295
	mCAA	6.67	(1.75-25.39)	0.006**	1.78	(0.95-3.33)	0.069
Parietal	pCAA	2.50	(1.25-5.00)	0.010*	1.38	(0.72-2.62)	0.328
	mCAA	4.74	(1.42-15.78)	0.012*	1.65	(0.85-3.18)	0.135
Occipital	pCAA	2.18	(0.74-6.47)	0.159	2.55	(1.35-4.83)	0.004**
	mCAA	6.27	(1.13-34.66)	0.036*	2.18	(1.11-4.27)	0.024*

There were not enough cases with capillary CAA or vasculopathy for statistical analysis. Significance at

^*p<0.05;

significance at

^**p<0.01;

significance at

^***p<0.001.