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. 2014 Mar 27;15:41. doi: 10.1186/1471-2156-15-41

Table 2.

Description of lead SNPs showing significant association with hematological traits by GWAS

Traits 1 Peak SNP Num 2 Chr 3 Pos (bp) 4 Nearest gene 5 Distance (bp) 6 P-value Var (%) 7
MCV**
 ss478944677
 75
 2
 55226096
 SH3BP5L
 Within
 3.00E-11
 19.41
MCH**
 ss131190955
 60
 2
 60227081
 CPAMD8
 Within
 1.36E-10
 7.91
RDW**
 ss107831331
 14
 2
 70061497
 CARM1
 Within
 2.10E-07
 14.13
MCHC*
 ss131046473
 22
 6
 49168322
 ELSPBP1
 65
 1.52E-06
 10.06
HCT*
 ss131276048
 5
 4
 104825883
 INTS3
 Within
 3.19E-06
 6.80
RBC*
 ss131276048
 4
 4
 104825883
 INTS3
 Within
 3.78E-06
 6.52
HGB*
 ss131493776
 1
 13
 11696883
 UBE2E1
 Within
 7.88E-06
 4.75
WBC*
 ss107857076
 2
 2
 105499649
 ENSSSCG00000030166
 95033
 6.03E-06
 8.66
P-LCR**
 ss107886044
 17
 2
 56469735
 TRIM58
 Within
 1.58E-07
 13.32
MPV* ss107886044 5 2 56469735 TRIM58 Within 2.49E-06 15.43

The associated region was defined as the interval the distances between two adjacent genome-wide significant SNPs was less than 10 Mb.

1The abbreviations of hematological traits are given in Table 1. e.g. MCV is Mean corpuscular volume.

2The number of significant SNPs for each hematological trait.

3, 4Chromosomal locations and positions of the most significant SNP associated with hematological traits in Sus scrofa Build 10.2 assembly.

5The nearest annotated gene to the significant SNP. The annotated gene database is from http://asia.ensembl.org/index.html.

6SNP designated as in a gene or distance (bp) from a gene region in Sus scrofa Build 10.2 assembly, “0” in column 6 represent un-annotated genes.

7the phenotype variance explained by the significant SNP.

**Genome-wide significant.

*Chromosome-wide significant.