Table 3.
Description of lead SNPs showing significant association with hematological traits by LDLA
| Traits 1 | Peak SNP | Num 2 | Chr 3 | Pos (bp) 4 | Nearest gene 5 | Distance (bp) 6 | P-value |
|---|---|---|---|---|---|---|---|
| HCT** |
ss107842725 |
331 |
7 |
24777963 |
ENSSSCG00000001232 |
Within |
1.28E-08 |
| RBC** |
ss107842725 |
180 |
7 |
24777963 |
ENSSSCG00000001232 |
Within |
1.20E-07 |
| MCH* |
ss478941323 |
60 |
5 |
61925570 |
GRIN2B |
144801 |
3.05E-06 |
| MCV* |
ss107842725 |
68 |
7 |
24777963 |
ENSSSCG00000001232 |
Within |
1.47E-06 |
| RDW-SD* |
ss131114130 |
13 |
9 |
33331814 |
ENSSSCG00000014974 |
3311 |
1.89E-05 |
| WBC* | ss131152863 | 1 | 1 | 289943447 | TLR4 | 157600 | 1.49E-05 |
The associated region was defined as the interval the distances between two adjacent genome-wide significant SNPs was less than 10 Mb.
1The abbreviations of hematological traits are given in Table 1. e.g. MCV is Mean corpuscular volume.
2The number of significant SNPs for each hematological trait.
3, 4Chromosomal locations and positions of the most significant SNP associated with hematological traits in Sus scrofa Build 10.2 assembly.
5The nearest annotated gene to the significant SNP. The annotated gene database is from http://asia.ensembl.org/index.html.
6SNP designated as in a gene or distance (bp) from a gene region in Sus scrofa Build 10.2 assembly, “0” in column 6 represent un-annotated genes.
**Genome-wide significant.
*Chromosome-wide significant.