Table 1.
Chr | SNP of interest | Alleles | Replacement SNP | Gene | Alleles | Risk Allele | MAF | OR |
---|---|---|---|---|---|---|---|---|
1 |
rs2651899 |
T > C |
|
PRMD16 |
|
C |
0.45 |
1.10 |
1 |
rs3790455 |
|
rs2274316 |
MEF2D |
A > C |
C |
0.34 |
1.23 |
2 |
rs10166942 |
|
rs1003540 |
TRMP8 |
A > G |
A |
Na |
Na |
3 |
rs7640543 |
|
rs4075749 |
TGFBR2 |
T > C |
C |
Na |
Na |
6 |
rs9349379 |
A > G |
|
PHACTR1 |
|
A |
0.38 |
0.82 |
8 |
rs1835740 |
C > T |
|
MTDH |
|
T |
0.22 |
1.0 |
9 |
rs6478241 |
G > A |
|
ASTN2 |
|
A |
0.38 |
1.22 |
12 | rs11172113 | T > C | LRP1 | T | 0.4 | 0.86 |
Chr = chromosome; SNP of interest = SNPs identified in previous GWAS, see article text for references; Replacement SNP = SNPs of interest not genotyped on the Illumina chip were replaced with other genotyped SNPs in linkage disequilibrium with the SNP of interest (r 2 > 0.89); Gene = the SNPs are either located within or close to these genes; MAF = minor allele frequency from Freilinger et al. [14]; OR = odds ratio from Freilinger et al. [14].