Table 2.
QC sample (ng/mL) | Compound A | Metabolite | ||||||||
LLOQ | LQC | MQC | HQC | ULOQ | LLOQ | LQC | MQC | HQC | ULOQ | |
10.8 | 22.1 | 276 | 2,300 | 2,730 | 3.17 | 6.72 | 84.0 | 700 | 811 | |
n | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 | 18 |
Mean | 11.5 | 22.9 | 290 | 2,350 | 2,680 | 3.36 | 6.98 | 84.9 | 721 | 835 |
CV (%) | 4.7 | 5.0 | 2.5 | 4.8 | 5.0 | 14.5 | 8.0 | 3.3 | 4.4 | 4.0 |
Bias (%) | 6.5 | 3.6 | 5.1 | 2.2 | -1.8 | 6.0 | 3.9 | 1.1 | 3.0 | 3.0 |