Table 6. Risk Estimates from Cox Proportional Hazard Analysis Based on the Three Continent AMD Consortium.

Variable	Code	Beta Coefficient per Code
Age	<65 = 0/65–75 = 1/75+ = 2	0/1.558/2.433
Sex	M = 0/F = 1	0/0.320
ARMS2 rs10490924	GG = 0/GT = 1/TT = 2	0/0.779/1.720
CFH rs800292	GG = 0/GA = 1/AA = 2	0/−0.899/−1.614
C2/CFB rs4151667	TT = 0/TA or AA = 1	0/−1.245
CFH rs12144939	GG = 0/GT = 1/TT = 2	0/−0.947/−1.195
COL8A1 rs13081855	GG = 0/GT = 1/TT = 2	0/0.223/0.890
C3 rs2230199	CC = 0/GC = 1/GG = 2	0/−0.033/0.755
SLC16A8 rs8135665	CC = 0/TC = 1/TT = 2	0/0.313/0.648
C3 rs433594	GG = 0/GA = 1/AA = 2	0/−0.110/−0.591
C2/CFB rs641153	GG = 0/GA or AA = 1	0/−0.592
SKIV2L rs429608	GG = 0/GA = 1/AA = 2	0/0.027/0.590
CETP rs3764261	CC = 0/CA = 1/AA = 2	0/0.215/0.478
ADAMTS9 rs6795735	CC = 0/TC = 1/TT = 2	0/0.130/0.424
RAD51B rs8017304	AA = 0/AG = 1/GG = 2	0/−0.414/−0.138
TIMP3 rs5749482	GG = 0/GC or CC = 1	0/−0.357
TGBR1 rs334353	TT = 0/TG = 1/GG = 2	0/0.039/−0.336
CFH rs1061170	TT = 0/TC = 1/CC = 2	0/0.175/0.278
FRK/COL10A1 rs3812111	TT = 0/TA = 1/AA = 2	0/−0.278/−0.118
CFI rs10033900	CC = 0/TC = 1/TT = 2	0/−0.070/−0.223
TNFRSF10A rs13278062	TT = 0/TG = 1/GG = 2	0/0.093/0.196
B3GALTL rs9542236	TT = 0/TC = 1/CC = 2	0/−0.231/−0.169
IER3/DDR1 rs3130783	AA = 0/AG = 1/GG = 2	0/0.029/0.166
MYRIP rs2679798	AA = 0/AG = 1/GG = 2	0/0.059/0.156
VEGFA rs943080	CC = 0/TC = 1/TT = 2	0/0/0.098
ABCA1 rs1883025	CC = 0/TC = 1/TT = 2	0/−0.046/0.076
LIPC rs12912415	AA = 0/AG or GG = 1	0/−0.098
LPL rs256	CC = 0/TC or TT = 1	0/−0.048
AMD baseline grade	Level 10 = 0/Level 20 = 1/Level 30 = 2/Level 40 = 3	0/1.458/2.560/3.398
Smoking	Never = 0/Past = 1/Current = 2	0/0.164/0.651
BMI (kg/m2)	<25 = 0/25+ = 1	0/0.007

AMD = age-related macular degeneration; BMI = body mass index; F = female; M = male.